RTNC2 Développement: RDC TV local chain

Allo Docteur Programme on RDC TV local Channel

Presentation of the NIDIAG activities with investigators from NIDIAG project. Please consult these 2 links: link1 and link 2.

Publications in peer-reviewed journals with acknowledgement of NIDIAG

Becker SL, Piraisoody N, Kramme S, Marti H, Silué KD, Panning M, Nickel B, Kern WV, Herrmann M, Hatz CF, N’Goran EK, Utzinger J, von Müller L. Real-time PCR for detection of Strongyloides stercoralis in human stool samples from Côte d’Ivoire: diagnostic accuracy, inter-laboratory comparison and patterns of hookworm co-infection. Acta Trop ; 150:210-217 [Epub ahead of print].

Becker SL, Chatigre JK, Coulibaly JT, Mertens P, Bonfoh B, Herrmann M, Kuijper EJ, N'Goran EK, Utzinger J, von Müller L. Molecular and culture-based diagnosis of Clostridium difficile isolates from Côte d'Ivoire after prolonged storage at disrupted cold chain conditions. Trans R Soc Trop Med Hyg. ;109(10):660-8. doi: 10.1093/trstmh/trv071. Epub Sep 8.

Becker SL, Chappuis F, Polman K, N'Goran EK, von Müller L, Utzinger J. Reply: epidemiological studies need asymptomatic controls. Clin Microbiol Infect (electronically published ahead of print),

Becker SL, Chatigre JK, Gohou JP, Coulibaly JT, Leuppi R, Polman K et al. Combined stool-based multiplex PCR and microscopy for enhanced pathogen detection in patients with persistent diarrhoea and asymptomatic controls from Côte d'Ivoire. Clin Microbiol Infect (electronically published ahead of print),

Utzinger J, Becker SL, van Lieshout L, van Dam GJ, Knopp S. New diagnostic tools in schistosomiasis. Clin Microbiol Infect (electronically published ahead of print),

Rogé S, Van Nieuwenhove L, Meul M, Heykers A, Brouwer de Koning A, Bebronne N, Guisez Y, Büscher P. Recombinant antigens expressed in Pichia pastoris for the diagnosis of sleeping sickness caused by Trypanosoma brucei gambiense. PLoS Negl Trop Dis; 8: e3006.

Bhattacharyya T, Ayandeh A, Falconar AK, Sundar S, El-Safi S, Gripenberg MA, Bowes DE, Thunissen C, Singh OP, Kumar R, Ahmed O, Eisa O, Saad A, Silva Pereira S, Boelaert M, Mertens P, Miles MA. IgG1 as a Potential Biomarker of Post-chemotherapeutic Relapse in Visceral Leishmaniasis, and Adaptation to a Rapid Diagnostic Test. PLoS Negl Trop Dis ; 8(10): e3273.

Bhattacharyya T, Bowes DE, El-Safi S, Sundar S, Falconar AK, Singh OP, Kumar R, Ahmed O, Boelaert M, Miles MA. Significantly lower anti-Leishmania IgG responses in Sudanese versus Indian visceral leishmaniasis. PLoS Negl Trop Dis ; 8(2): e2675.

Bottieau E, Mukendi D, Kalo JR, Mpanya A, Lutumba P, Barbé B, Chappuis F, Lunguya O, Boelaert M, Jacobs J. Fatal Chromobacterium violaceum bacteraemia in rural Bandundu, Democratic Republic of the Congo. New Microbes New Infect.

Büscher P, Mertens P, Leclipteux T, Gilleman Q, Jacquet D, Mumba-Ngoyi D, Pyana PP, Boelaert M, Lejon V. Sensitivity and specificity of HAT Sero-K-SeT, a rapid diagnostic test for serodiagnosis of sleeping sickness caused by Trypanosoma brucei gambiense: a case-control study. Lancet Glob Health ; 2(6): e359-63.

Mpanya A, Boelaert M, Baloji S, Matangila J, Lubanza S, Bottieau E, Chappuis F, Lutumba P, Hendrickx D. Diagnostic work-up of neurological syndromes in a rural African setting: knowledge, attitudes and practices of health care providers. PLoS One; 9(10): e110167.

Becker SL, Vogt J, Knopp S, Panning M, Warhurst DC, Polman K, Marti H, von Müller L, Yansouni CP, Jacobs J, Bottieau E, Sacko M, Rijal S, Meyanti F, Miles MA, Boelaert M, Lutumba P, van Lieshout L, N'Goran EK, Chappuis F, Utzinger J. Persistent digestive disorders in the tropics: causative infectious pathogens and reference diagnostic tests. BMC Infect Dis; 13: 37.

Bhattacharyya T, Boelaert M, Miles MA. Comparison of visceral leishmaniasis diagnostic antigens in African and Asian Leishmania donovani reveals extensive diversity and region-specific polymorphisms. PLoS Negl Trop Dis ; 7(2): e2057.

Büscher P, Mumba Ngoyi D, Pyana PP, Mertens P, Leclipteux T, Gilleman Q, Camara O, Camara M, Leno M, Sakande H, Dama D, Bucheton B, Jamonneau V, Lejon V. New rapid tests for antibody detection serodiagnosis in Trypanosoma brucei gambiense sleeping sickness. HAT Platform Newsletter; 13: 21-22.

Büscher P, Gilleman Q, Lejon V. Rapid diagnostic tests for sleeping sickness. N Engl J Med; 368(11): 1069.

Chappuis F, Alirol E, d'Acremont V, Bottieau E, Yansouni CP. Rapid diagnostic tests for non-malarial febrile illness in the tropics. Clin Microbiol Infect ; 19(5): 422-31.

Fürst T, Silué KD, Ouattara M, Adiossan LG, N'Goran DN, Yao AJ, Koné S, N'Goran EK, Utzinger J, Bogoch II. Patients routinely report more symptoms to experienced field enumerators than physicians in rural Cote d'Ivoire. Am J Trop Med Hyg ; 89(3): 592-6.

Knopp S, Becker SL, Ingram KJ, Keiser J, Utzinger J. Diagnosis and treatment of schistosomiasis in children in the era of intensified control. Expert Rev Anti Infect Ther ; 11(11):1237-58.

Meheus F, Abuzaid AA, Baltussen R, Younis BM, Balasegaram M, Khalil EA, Boelaert M, Musa AM. The economic burden of visceral leishmaniasis in Sudan: an assessment of provider and household costs. Am J Trop Med Hyg; 89(6): 1146-53.

Yansouni CP, Bottieau E, Lutumba P, Winkler AS, Lynen L, Büscher P, Jacobs J, Gillet P, Lejon V, Alirol E, Polman K, Utzinger J, Miles MA, Peeling RW, Muyembe JJ, Chappuis F, Boelaert M. Rapid diagnostic tests for neurological infections in central Africa. Lancet Infect Dis; 13(6): 546-58.

Yansouni CP, Bottieau E, Chappuis F, Phoba MF, Lunguya O, Ifeka BB, Jacobs J. Rapid diagnostic tests for a coordinated approach to fever syndromes in low-resource settings. Clin Infect Dis 55(4): 610-1 (letter); 611-2 (author reply).

Related publications in peer-reviewed journals without acknowledgement of NIDIAG

Bottieau E. Point-of-care testing: filling the diagnostic gaps in tropical medicine? Clin Microbiol Infect 19(5): 397-8.

Uranw S, Meheus F, Baltussen R, Rijal S, Boelaert M. The household costs of visceral leishmaniasis care in south-eastern Nepal. PLoS Negl Trop Dis 7(2): e2062.

Presentations at international meetings with acknowledgement of NIDIAG: oral sessions

Verdonck K. Clinical spectrum, main etiologies and outcome of neurological disorders in the rural Hospital of Mosango, Province of Bandundu, Democratic Republic of the Congo. Oral session presented at: 9th European Congress on Tropical Medicine and International Health; Basel, Switzerland.

Meheus F. Diagnostic guidance for patients presenting with persistent fever in neglected tropical disease endemic areas of Cambodia, the Democratic Republic of Congo, Nepal and Sudan. Oral session presented at: 9th European Congress on Tropical Medicine and International Health; Basel, Switzerland.

Becker S. Stool-based polymerase chain reaction for the diagnosis of multiple pathogens in Mali: a case-control study. Oral session presented at: 9th European Congress on Tropical Medicine and International Health; Basel, Switzerland.

Chappuis F. Diagnostic guidance for patients presenting with persistent fever in neglected tropical disease endemic areas of Cambodia, the Democratic Republic of Congo, Nepal and Sudan. Oral session presented at: 9th European Congress on Tropical Medicine and International Health; Basel, Switzerland.

Bottieau E. Clinical spectrum, main etiologies and outcome of neurological disorders in the rural Hospital of Mosango, Province of Bandundu, Democratic Republic of the Congo. Oral session presented at: 9th European Congress on Tropical Medicine and International Health; Basel, Switzerland.

Q. Gilleman. Development of a rapid diagnostic test for active case detection in sleeping sickness control: recHAT Sero-Strip. Oral session presented at: 9th European Congress on Tropical Medicine and International Health; Basel, Switzerland.

Chappuis F. From a disease-specific to a syndromic diagnostic approach: the cases of visceral leishmaniasis and human African trypanosomiasis. Oral session presented at: ASTMH, 63rd Annual Meeting; New Orleans, USA.

El Safi S. The Role of Rapid Diagnostic Tests (RDTs) in Improving the Clinical Management of Patients Presenting with Chronic Fever. Oral session presented at: ASLM, 2nd international conference;; Cape Town, South Africa.

Jacobs J. Quality Issues in RDTs for Neglected Infectious Diseases. Oral session presented at: ASLM, 2nd international conference; Cape Town, South Africa.

Lutumba P, Sacko M. The Role of RDTs in Improving the Clinical Management of Patients Presenting with Neurological Syndrome. Oral session presented at: ASLM, 2nd international conference; Cape Town, South Africa.

Roge S. Diagnosis of human African trypanosomiasis with antigens expressed in Pichia pastoris. Oral presentation at: Pichia expression conference; San Diego, California, USA.

Bhattacharyya T. Understanding differential regional sensitivity of rapid diagnosis for visceral leishmaniasis. Oral session presented at: WorldLeish5; Porto de Galinhas, Brazil.

Büscher P, Mertens P, Leclipteux T, Gilleman Q, Jacquet D, Mumba Ngoyi D, Pyana PP, Menten J, Lejon V. Diagnostic accuracy under field conditions of HAT Sero K-Set, a rapid diagnostic test for sleeping sickness. Oral session presented at: BSP Autumn Symposium, Advances in diagnostics for infectious diseases; Liverpool, UK.

Büscher P, Mertens P, Leclipteux T, Gilleman Q, Jacquet D, Mumba-Ngoyi D, Pyana PP, Menten J, Lejon V. Diagnostic accuracy under field conditions of HAT Sero K-SeT, a rapid diagnostic test for sleeping sickness. Oral session presented at: 32nd ISCTRC meeting; Khartoum, Sudan.

Büscher P, Mertens P, Leclipteux T, Gilleman Q, Jacquet D, Mumba Ngoyi D, Pyana PP, Menten J, Lejon V. Diagnostic accuracy under field conditions of HAT Sero K-SeT, a rapid diagnostic test for sleeping sickness. Oral session presented at: DNDi Africa. A decade of R&D for neglected diseases in Africa. Endemic country research and development for patient access; Nairobi, Kenya.

Mumba Ngoyi D, Gilleman Q, Pyana P, Lejon V, Menten J, Büscher P. Les nouveaux tests de diagnostic rapide pour la THA à T.b.gambiense. Oral session presented at: CIPIP - 6th International Congress on Infectious and Parasitic Diseases; Kinshasa, DRC. Ann Afr Med; 6(1,4).

Mukendi D, Kalo JR, Bottieau E, Barbe B, Gillet P, Mpanya A, Yansouni CP, Winkler A, Muyembe JJ, Jacobs J, Chappuis F, Boelart M, Lutumba P. Résultats préliminaires de l’étude neurologique NIDIAG explorant les causes d’affections neurologiques à l’Hôpital Général de Référence de Mosango, Province de Bandundu, République Démocratique du Congo. Oral session presented at: CIPIP - 6th International Congress on Infectious and Parasitic Diseases; Kinshasa, DRC. Ann Afr Med 6(2).

Büscher P. Tools for elimination: screening and diagnostic tools. Oral session presented at: WHO meeting on human African trypanosomiasis (T.b. gambiense) elimination; Geneva, Switzerland.

Büscher P. Sleeping sickness epidemiology and control: current status and perspectives for the near future. Oral session presented at: XVIII International Congress for Tropical Medicine and Malaria and XLVIII Congress of the Brazilian Society of Tropical Medicine; Rio de Janeiro, Brazil.

Presentations at international meetings with acknowledgement of NIDIAG: poster sessions

Becker S, Yap P. Parasitological characterisation of persistent digestive disorders in Mali: a case-control study. Poster session presented at: 9th European Congress on Tropical Medicine and International Health; Basel, Switzerland.

Meheus F, Burza S. The cost and cost-effectiveness of IgG1 as point-of-care rapid diagnostic tests to detect relapse of visceral leishmaniasis. Poster session presented at: 9th European Congress on Tropical Medicine and International Health;; Basel, Switzerland.

Becker J et al. Luminex® xTAG GPP multiplex PCR assay for the diagnosis of gastrointestinal pathogens: preliminary findings from a case-control study in Côte d'Ivoire. Poster session presented at: 65th Annual Meeting of the German Society for Hygiene and Microbiology (DGHM); Rostock, Germany.

Piraisoody N, Kramme S, Marti H, Silué KD, Panning M, Herrmann M, Hatz CF, N’Goran EK, Utzinger J, von Müller L, Becker SL. Diagnostic accuracy and inter-laboratory comparison of microscopy and real-time PCR for detection of Strongyloides stercoralis. Poster session presented at: 66th Annual Meeting of the German Society of Hygiene and Microbiology; Dresden, Germany.

Traore M. Syndromic approach to neglected infectious diseases (NID) at primary health care level: an international collaboration on integrated diagnosis-treatment platforms. Poster session presented at: ASTMH, 63rd Annual Meeting; New Orleans, USA.

Bottieau E, Mukendi D, Kalo JR, Barbe B, Gillet P, Mpanya A, Yansouni CP, Winkler A, Lutumba P, Jacobs J, Chappuis F, Boelart M, Lutumba P. Etiology and outcome of neurological disorders in the Rural Hospital of Mosango, Province of Bandundu, Democratic Republic of Congo: preliminary results. Poster session presented at: 8th European Congress on Tropical Medicine and International Health & 5th Conference of the Scandinavian-Baltic Society for Parasitology; Copenhagen, Denmark.

Camara O, Camara M, Sakande H, Leno M, Dama E, Gilleman Q, Büscher P, Bucheton B, Jamonneau V, Lejon V. Preliminary evaluation of the diagnostic performance of the HAT Sero-K-Set rapid diagnostic test in Guinea. Poster session presented at: 32nd ISCTRC meeting; Khartoum, Sudan.

Rogé S, Meul M, Guisez Y, Gilleman Q, Simon T, Büscher P. Development of rapid diagnostic tests for surra and sleeping sickness based on recombinant variant surface glycoproteins. Poster session presented at: BSP Autumn Symposium, Advances in diagnostics for infectious diseases; Liverpool, UK.

Gilleman Q, Mertens P, Büscher P. Development of a Rapid Diagnostic Test for detection of sleeping sickness. Poster session presented at: Science For Business, BioWin, Innovation of the economy and innovation of the patients; Louvain-la-Neuve, Belgium.

Rogé S, Meul M, Guisez Y, Gilleman Q, Simon T, Büscher P. Development of rapid diagnostic tests for surra and sleeping sickness based on recombinant antigens expressed in Pichia pastoris. Poster session presented at: Pathogens’ survival strategies, from fundamentals to field. ITM 54th International Colloquium; Antwerp, Belgium.

Other media releases with acknowledgement of NIDIAG

NIDIAG A guide to spotting forgotten diseases. Investing in European success - EU-Africa cooperation in science, technology and innovation. Internet publication;.

NIDIAG Une assistance pour diagnostiquer les maladies «oubliées». Investir dans la réussite européenne - Coopération entre l’Union européenne et l’Afrique dans le domaine des sciences, des technologies et de l’innovation. Internet publication;.

NIDIAG Um guia para detetar doenças esquecidas. Investir no sucesso europeu - Cooperação UE-África nos domínios da ciência, tecnologia e inovação. Internet publication;.

EU fighting neglected infectious diseases and training local health professionals in least developed countries. Internet publication;.

Boelaert M, Lutumba P, Chappuis F, Sacko M. Allo Docteur, RTNC2 Développement (Radio et Télévision Nationale du Congo). Interview on NID; Kinshasa, DRC.

Büscher P. Allo Docteur, RTNC2 Développement (Radio et Télévision Nationale du Congo). Interview on the HAT Sero-K-SeT; Kinshasa, DRC.

Büscher P. Nouveau test rapide pour le diagnostic de la maladie du sommeil. Press release; Kinshasa, DRC.

Büscher P. Feu vert pour un test rapide pour la maladie du sommeil. Internet publication;